The Mechanism of Gene Expression and Gene Regulation

The Mechanism of Gene Expression and Gene Regulation

Date(s) & Location(s):
June 9 - 14, 2024 in Durham, NC
Grades Eligible:
Rising  7th 8th 9th
Course Description:

Embark on a journey into gene expression, a crucial process converting genetic information into functional proteins for proper cell and organism development. Explore the binding of regulatory proteins to DNA motifs, the influence of transcription factors, and the assembly of transcriptional machinery led by RNA polymerase at gene promoters.

Follow the progression from primary transcript (pre-mRNA) synthesis to mature mRNA through processing steps. Investigate factors affecting gene expression rates, including transcription factor availability, DNA accessibility, and regulatory molecules.

Uncover the impact of chromatin structure on gene modulation, differentiating between silencing heterochromatin and expression-friendly euchromatin. This course provides essential insights into gene expression and regulation, offering a foundational understanding of cell biology and genetics. Join us to unravel the molecular intricacies that shape cellular function.

Sarmistha Ghosh
About The Instructor:

Sarmistha Ghosh, with an MS in Biochemistry, is an AP Biology teacher at a Charlotte Mecklenburg Schools. A Science Leader for CMS Science Teaching and Learning, she’s recognized as a 2024-2026 NC Science Leadership Association Fellow. Sarmistha conducted research on Comparative Micromorphology at Iowa University as part of the RET program. A 2023-2024 NC Energy Literacy Fellow, she presented at the 2024 K-12 STEM Conference, UNC Charlotte. Her commitment to professional development is evident in her role in CMS training for science teachers.